ITT3008
ITT3008
- Catalog: ITT3008
- Gene/Protein: NDUFA4
- Product Description: Immunotag™ NDUFA4 Polyclonal Antibody
385.0000
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Antibody Specification | |
Datasheet | |
Target Protein | NDUFA4 |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,IHC-p,ELISA |
Recommended Dilution | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications. |
Concentration | 1 mg/ml |
Reactive Species | Human,Mouse,Rat |
Host Species | Rabbit |
Immunogen | The antiserum was produced against synthesized peptide derived from human NDUFA4. AA range:32-81 |
Specificity | NDUFA4 Polyclonal Antibody detects endogenous levels of NDUFA4 protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Gene Name | NDUFA4 |
Accession No. | O00483 Q62425 |
Alternate Names | NDUFA4; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4; Complex I-MLRQ; CI-MLRQ; NADH-ubiquinone oxidoreductase MLRQ subunit |
Description | NDUFA4, mitochondrial complex associated(NDUFA4) Homo sapiens The protein encoded by this gene belongs to the complex I 9kDa subunit family. Mammalian complex I of mitochondrial respiratory chain is composed of 45 different subunits. This protein has NADH dehydrogenase activity and oxidoreductase activity. It transfers electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. [provided by RefSeq, Jul 2008], |
Cell Pathway/ Category | Oxidative phosphorylation,Alzheimer's disease,Parkinson's disease,Huntington's disease, |
Protein Expression | Brain,Liver, |
Subcellular Localization | mitochondrion,mitochondrial inner membrane,mitochondrial respiratory chain complex I,mitochondrial respiratory chain complex IV,integral component of membrane,extracellular exosome, |
Protein Function | function:Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed to be not involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.,similarity:Belongs to the complex I NDUFA4 subunit family.,subunit:Mammalian complex I is composed of 45 different subunits., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |