ITT3018
ITT3018
- Catalog: ITT3018
- Gene/Protein: NDUFS3
- Product Description: Immunotag™ NDUFS3 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | NDUFS3 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse |
| Host Species | Rabbit |
| Immunogen | The antiserum was produced against synthesized peptide derived from human NDUFS3. AA range:117-166 |
| Specificity | NDUFS3 Polyclonal Antibody detects endogenous levels of NDUFS3 protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | NDUFS3 |
| Accession No. | O75489 Q9DCT2 |
| Alternate Names | NDUFS3; NADH dehydrogenase [ubiquinone] iron-sulfur protein 3; mitochondrial; Complex I-30kD; CI-30kD; NADH-ubiquinone oxidoreductase 30 kDa subunit |
| Description | NADH:ubiquinone oxidoreductase core subunit S3(NDUFS3) Homo sapiens This gene encodes one of the iron-sulfur protein (IP) components of mitochondrial NADH:ubiquinone oxidoreductase (complex I). Mutations in this gene are associated with Leigh syndrome resulting from mitochondrial complex I deficiency.[provided by RefSeq, Apr 2009], |
| Cell Pathway/ Category | Oxidative phosphorylation,Alzheimer's disease,Parkinson's disease,Huntington's disease, |
| Protein Expression | Brain,Cajal-Retzius cell,Pituitary,Skin,Stomach mucosa,Uter |
| Subcellular Localization | nucleus,mitochondrion,mitochondrial respiratory chain complex I,mitochondrial matrix,mitochondrial membrane,myelin sheath, |
| Protein Function | catalytic activity:NADH + acceptor = NAD(+) + reduced acceptor.,catalytic activity:NADH + ubiquinone = NAD(+) + ubiquinol.,function:Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.,similarity:Belongs to the complex I 30 kDa subunit family.,subunit:Mammalian complex I is composed of 45 different subunits., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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