ITT3023
ITT3023
- Catalog: ITT3023
- Gene/Protein: NDUFV3
- Product Description: Immunotag™ NDUFV3 Polyclonal Antibody
385.0000
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Antibody Specification | |
Datasheet | |
Target Protein | NDUFV3 |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | IHC-p,ELISA |
Recommended Dilution | Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications. |
Concentration | 1 mg/ml |
Reactive Species | Human |
Host Species | Rabbit |
Immunogen | The antiserum was produced against synthesized peptide derived from human NDUFV3. AA range:26-75 |
Specificity | NDUFV3 Polyclonal Antibody detects endogenous levels of NDUFV3 protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Gene Name | NDUFV3 |
Accession No. | P56181 Q8BK30 |
Alternate Names | NDUFV3; NADH dehydrogenase [ubiquinone] flavoprotein 3; mitochondrial; Complex I-9kD; CI-9kD; NADH-ubiquinone oxidoreductase 9 kDa subunit; Renal carcinoma antigen NY-REN-4 |
Description | NADH:ubiquinone oxidoreductase subunit V3(NDUFV3) Homo sapiens The protein encoded by this gene is one of at least forty-one subunits that make up the NADH-ubiquinone oxidoreductase complex. This complex is part of the mitochondrial respiratory chain and serves to catalyze the rotenone-sensitive oxidation of NADH and the reduction of ubiquinone. The encoded protein is one of three proteins found in the flavoprotein fraction of the complex. The specific function of the encoded protein is unknown. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008], |
Cell Pathway/ Category | Oxidative phosphorylation,Alzheimer's disease,Parkinson's disease,Huntington's disease, |
Protein Expression | Brain,Renal cell carcinoma, |
Subcellular Localization | nucleoplasm,mitochondrion,mitochondrial inner membrane,mitochondrial respiratory chain complex I, |
Protein Function | function:Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed to be not involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.,similarity:Belongs to the complex I NDUFV3 subunit family.,subunit:Complex I is composed of 45 different subunits. This is a component of the flavoprotein-sulfur (FP) fragment of the enzyme., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |