ITT3031
ITT3031
- Catalog: ITT3031
- Gene/Protein: NEIL3
- Product Description: Immunotag™ NEIL3 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | NEIL-3 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,IHC-p,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse |
| Host Species | Rabbit |
| Immunogen | The antiserum was produced against synthesized peptide derived from human NEIL3. AA range:491-540 |
| Specificity | NEIL3 Polyclonal Antibody detects endogenous levels of NEIL3 protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | NEIL3 |
| Accession No. | Q8TAT5 Q8K203 |
| Alternate Names | NEIL3; Endonuclease 8-like 3; DNA glycosylase FPG2; DNA glycosylase/AP lyase Neil3; Endonuclease VIII-like 3; Nei-like protein 3 |
| Description | nei like DNA glycosylase 3(NEIL3) Homo sapiens NEIL3 belongs to a class of DNA glycosylases homologous to the bacterial Fpg/Nei family. These glycosylases initiate the first step in base excision repair by cleaving bases damaged by reactive oxygen species and introducing a DNA strand break via the associated lyase reaction (Bandaru et al., 2002 [PubMed 12509226]).[supplied by OMIM, Mar 2008], |
| Cell Pathway/ Category | Base excision repair, |
| Protein Expression | B-cell,Skin, |
| Subcellular Localization | nucleus,nucleoplasm, |
| Protein Function | function:Reports about DNA glycosylase activity are contradictory. The protein lacks a proline residue at the N-terminus that is the active site residue found in the other members of the FPG family.,similarity:Belongs to the FPG family.,similarity:Contains 1 FPG-type zinc finger.,similarity:Contains 1 RanBP2-type zinc finger.,tissue specificity:Detected in thymus and testis., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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