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ITT3040

ITT3040
  • Catalog: ITT3040
  • Gene/Protein: ELK3
  • Product Description: Immunotag™ Net Polyclonal Antibody
385.0000
Price in reward points: 385

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Immunotag™ Net Polyclonal Antibody
Antibody Specification
Datasheet
Target Protein Net
Clonality Polyclonal
Storage/Stability -20°C/1 year
Application IF,ELISA
Recommended Dilution Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
Concentration 1 mg/ml
Reactive Species Human,Mouse
Host Species Rabbit
Immunogen The antiserum was produced against synthesized peptide derived from human Elk3. AA range:323-372
Specificity Net Polyclonal Antibody detects endogenous levels of Net protein.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Gene Name ELK3
Accession No. P41970 P41971
Alternate Names ELK3; NET; SAP2; ETS domain-containing protein Elk-3; ETS-related protein ERP; ETS-related protein NET; Serum response factor accessory protein 2; SAP-2; SRF accessory protein 2
Description ELK3, ETS transcription factor(ELK3) Homo sapiens This gene encodes a member of the ETS-domain transcription factor family and the ternary complex factor (TCF) subfamily. Proteins in this subfamily regulate transcription when recruited by serum response factor to bind to serum response elements. This protein is activated by signal-induced phosphorylation; studies in rodents suggest that it is a transcriptional inhibitor in the absence of Ras, but activates transcription when Ras is present. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015],
Protein Expression Brain,Epithelium,Placenta,
Subcellular Localization nucleus,nucleoplasm,mitochondrion,intracellular membrane-bounded organelle,
Protein Function function:May be a negative regulator of transcription, but can activate transcription when coexpressed with Ras, Src or Mos. Forms a ternary complex with the serum response factor and the ETS and SRF motifs of the Fos serum response element.,similarity:Belongs to the ETS family.,similarity:Contains 1 ETS DNA-binding domain.,subunit:Interacts with CTBP1.,
Usage For Research Use Only! Not for diagnostic or therapeutic procedures.
Material Safety Data Sheet
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