ITT3072
ITT3072
- Catalog: ITT3072
- Gene/Protein: OXT
- Product Description: Immunotag™ Neurophysin I Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | Neurophysin I |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,IHC-p,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Rat |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from the Internal region of human Neurophysin I |
| Specificity | Neurophysin I Polyclonal Antibody detects endogenous levels of Neurophysin I protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | OXT |
| Accession No. | P01178 P35454 P01179 |
| Alternate Names | OXT; OT; Oxytocin-neurophysin 1; OT-NPI |
| Description | oxytocin/neurophysin I prepropeptide(OXT) Homo sapiens This gene encodes a precursor protein that is processed to produce oxytocin and neurophysin I. Oxytocin is a posterior pituitary hormone which is synthesized as an inactive precursor in the hypothalamus along with its carrier protein neurophysin I. Together with neurophysin, it is packaged into neurosecretory vesicles and transported axonally to the nerve endings in the neurohypophysis, where it is either stored or secreted into the bloodstream. The precursor seems to be activated while it is being transported along the axon to the posterior pituitary. This hormone contracts smooth muscle during parturition and lactation. It is also involved in cognition, tolerance, adaptation and complex sexual and maternal behaviour, as well as in the regulation of water excretion and cardiovascular functions. [provided by RefSeq, Dec 2013], |
| Protein Expression | Lung, |
| Subcellular Localization | extracellular region,extracellular space,secretory granule,terminal bouton, |
| Protein Function | function:Neurophysin 1 specifically binds oxytocin.,function:Oxytocin causes contraction of the smooth muscle of the uterus and of the mammary gland.,online information:Oxytocin entry,pharmaceutical:Oxytocin is available under the names Pitocin (Parke-Davis) and Syntocinon (Sandoz). Used to artificially speed or induce labor.,similarity:Belongs to the vasopressin/oxytocin family., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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