ITT3082
ITT3082
- Catalog: ITT3082
- Gene/Protein: NFATC2IP
- Product Description: Immunotag™ NFATc2IP Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | NFATc2IP |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human |
| Host Species | Rabbit |
| Immunogen | The antiserum was produced against synthesized peptide derived from human NFATC2IP. AA range:151-200 |
| Specificity | NFATc2IP Polyclonal Antibody detects endogenous levels of NFATc2IP protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | NFATC2IP |
| Accession No. | Q8NCF5 O09130 |
| Alternate Names | NFATC2IP; NIP45; NFATC2-interacting protein; 45 kDa NF-AT-interacting protein; 45 kDa NFAT-interacting protein; Nuclear factor of activated T-cells; cytoplasmic 2-interacting protein |
| Description | function:Plays a role in the inducible expression of cytokine genes in T-cells, especially by increasing NFAT-driven IL-4 production.,PTM:Methylation at the N-terminus by PRMT1 modulates interaction with the NFAT complex and results in augmented cytokine production.,similarity:Contains 1 ubiquitin-like domain.,subcellular location:TRAF1 is associated with a fraction of NFATC2IP in the cytoplasm and prevents its translocation to the nucleus.,subunit:Interacts with NFATC2, TRAF1, TRAF2 and PRMT1., |
| Protein Expression | Brain,Epithelium,Eye,Liver, |
| Subcellular Localization | nucleus,cytoplasm, |
| Protein Function | function:Plays a role in the inducible expression of cytokine genes in T-cells, especially by increasing NFAT-driven IL-4 production.,PTM:Methylation at the N-terminus by PRMT1 modulates interaction with the NFAT complex and results in augmented cytokine production.,similarity:Contains 1 ubiquitin-like domain.,subcellular location:TRAF1 is associated with a fraction of NFATC2IP in the cytoplasm and prevents its translocation to the nucleus.,subunit:Interacts with NFATC2, TRAF1, TRAF2 and PRMT1., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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