ITT3118
ITT3118
- Catalog: ITT3118
- Gene/Protein: SLC9A7
- Product Description: Immunotag™ NHE-7 Polyclonal Antibody
385.0000
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Antibody Specification | |
Datasheet | |
Target Protein | NHE-7 |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,ELISA |
Recommended Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications. |
Concentration | 1 mg/ml |
Reactive Species | Human,Mouse,Rat |
Host Species | Rabbit |
Immunogen | The antiserum was produced against synthesized peptide derived from human SLC9A7. AA range:531-580 |
Specificity | NHE-7 Polyclonal Antibody detects endogenous levels of NHE-7 protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Gene Name | SLC9A7 |
Accession No. | Q96T83 Q8BLV3 |
Alternate Names | SLC9A7; NHE7; Sodium/hydrogen exchanger 7; Na(+)/H(+) exchanger 7; NHE-7; Solute carrier family 9 member 7 |
Description | solute carrier family 9 member A7(SLC9A7) Homo sapiens This gene encodes a sodium and potassium/ proton antiporter that is a member of the solute carrier family 9 protein family. The encoded protein is primarily localized to the trans-Golgi network and is involved in maintaining pH homeostasis in organelles along the secretory and endocytic pathways. This protein may enhance cell growth of certain breast tumors. This gene is part of a gene cluster on chromosome Xp11.23. A pseudogene of this gene is found on chromosome 12. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Mar 2012], |
Subcellular Localization | Golgi membrane,trans-Golgi network,plasma membrane,integral component of membrane,recycling endosome membrane, |
Protein Function | function:Mediates electroneutral exchange of protons for Na(+) and K(+) across endomembranes. May contribute to Golgi volume and cation homeostasis.,miscellaneous:Is not inhibited by amiloride but by benzamil and quinine.,similarity:Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.,subunit:Interacts with SCAMP1, SCAMP2 and SCAMP5; may participate in its shuttling from trans-Golgi network to recycling endosomes.,tissue specificity:Ubiquitously expressed., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |