ITT3155
ITT3155
- Catalog: ITT3155
- Gene/Protein: GRIN2D
- Product Description: Immunotag™ NMDAε4 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
|
| Target Protein | NMDAε4 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse,Rat,Monkey |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from NMDAε4, at AA range: 640-720 |
| Specificity | NMDAε4 Polyclonal Antibody detects endogenous levels of NMDAε4 protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | GRIN2D |
| Accession No. | O15399 Q03391 Q62645 |
| Alternate Names | GRIN2D; GluN2D; NMDAR2D; Glutamate [NMDA] receptor subunit epsilon-4; EB11; N-methyl D-aspartate receptor subtype 2D; NMDAR2D; NR2D |
| Description | glutamate ionotropic receptor NMDA type subunit 2D(GRIN2D) Homo sapiens N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate receptors. NMDA channel has been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of the key receptor subunit NMDAR1 (GRIN1) and 1 or more of the 4 NMDAR2 subunits: NMDAR2A (GRIN2A), NMDAR2B (GRIN2B), NMDAR2C (GRIN2C), and NMDAR2D (GRIN2D). [provided by RefSeq, Mar 2010], |
| Cell Pathway/ Category | Calcium,Neuroactive ligand-receptor interaction,Long-term potentiation,Alzheimer's disease,Amyotrophic lateral sclerosis (ALS), |
| Protein Expression | Brain,Fetal brain, |
| Subcellular Localization | intracellular,plasma membrane,integral component of membrane,NMDA selective glutamate receptor complex,cell junction,postsynaptic membrane, |
| Protein Function | function:NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine.,similarity:Belongs to the glutamate-gated ion channel (TC 1.A.10) family.,subunit:Interacts with PDZ domains of INADL and DLG4 (By similarity). Forms heteromeric channel of a zeta subunit (GRIN1), a epsilon subunit (GRIN2A, GRIN2B, GRIN2C or GRIN2D) and a third subunit (GRIN3A or GRIN3B)., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
| English_US |
|
| Danish |
|
| Dutch |
|
| English_UK |
|
| French |
|
| German |
|
| Spanish |
|
| Norwegian |
|
| Portuguese |
|
| Finnish |
|
| Swedish |
|
| Polish |
|