ITT3198
ITT3198
- Catalog: ITT3198
- Gene/Protein: NT5C1A
- Product Description: Immunotag™ NT5C1A Polyclonal Antibody
385.0000
Price in reward points: 385
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Antibody Specification | |
Datasheet | |
Target Protein | NT5C1A |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,IF,ELISA |
Recommended Dilution | Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications. |
Concentration | 1 mg/ml |
Reactive Species | Human,Mouse |
Host Species | Rabbit |
Immunogen | The antiserum was produced against synthesized peptide derived from human NT5C1A. AA range:151-200 |
Specificity | NT5C1A Polyclonal Antibody detects endogenous levels of NT5C1A protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Gene Name | NT5C1A |
Accession No. | Q9BXI3 A3KFX0 |
Alternate Names | NT5C1A; Cytosolic 5'-nucleotidase 1A; cN1A; Cytosolic 5'-nucleotidase IA; cN-I; cN-IA |
Description | 5'-nucleotidase, cytosolic IA(NT5C1A) Homo sapiens Cytosolic nucleotidases, such as NT5C1A, dephosphorylate nucleoside monophosphates (Hunsucker et al., 2001 [PubMed 11133996]).[supplied by OMIM, Mar 2008], |
Cell Pathway/ Category | Purine metabolism,Pyrimidine metabolism,Nicotinate and nicotinamide metabolism, |
Protein Expression | Heart, |
Subcellular Localization | cytosol, |
Protein Function | catalytic activity:A 5'-ribonucleotide + H(2)O = a ribonucleoside + phosphate.,cofactor:Magnesium.,enzyme regulation:Activated by ADP.,function:Dephosphorylates the 5' and 2'(3')-phosphates of deoxyribonucleotides and has a broad substrate specificity. Helps to regulate adenosine levels in heart during ischemia and hypoxia.,similarity:Belongs to the 5'-nucleotidase type 3 family.,tissue specificity:Highly expressed in skeletal muscle. Detected at intermediate levels in heart, brain, kidney and pancreas., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |