ITT3210
ITT3210
- Catalog: ITT3210
- Gene/Protein: NUMA1
- Product Description: Immunotag™ NuMA Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | NuMA |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,IHC-p,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human |
| Host Species | Rabbit |
| Immunogen | The antiserum was produced against synthesized peptide derived from human NUMA1. AA range:334-383 |
| Specificity | NuMA Polyclonal Antibody detects endogenous levels of NuMA protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | NUMA1 |
| Accession No. | Q14980 |
| Alternate Names | NUMA1; NUMA; Nuclear mitotic apparatus protein 1; NuMA protein; SP-H antigen |
| Description | nuclear mitotic apparatus protein 1(NUMA1) Homo sapiens This gene encodes a large protein that forms a structural component of the nuclear matrix. The encoded protein interacts with microtubules and plays a role in the formation and organization of the mitotic spindle during cell division. Chromosomal translocation of this gene with the RARA (retinoic acid receptor, alpha) gene on chromosome 17 have been detected in patients with acute promyelocytic leukemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2013], |
| Protein Expression | Brain,Epithelium,Kidney,Lung,Muscle,Ovary,Testis,Uterus, |
| Subcellular Localization | Golgi membrane,spindle pole,nucleus,nucleoplasm,chromosome,cytoplasm,centrosome,spindle,cytosol,spindle microtubule,cell cortex,nuclear matrix,dendrite,neuronal cell body,apical p |
| Protein Function | function:May be a structural component of the nucleus.,subcellular location:Dissociates from condensing chromosomes during early prophase, before the complete disintegration of the nuclear lamina. As mitosis progresses it reassociates with telophase chromosomes very early during nuclear reformation, before substantial accumulation of lamins on chromosomal surfaces is evident., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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