ITT3471
ITT3471
- Catalog: ITT3471
- Gene/Protein: HCRTR1
- Product Description: Immunotag™ Orexin R-1 Polyclonal Antibody
385.0000
Price in reward points: 385
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Antibody Specification | |
Datasheet | |
Target Protein | Orexin R-1 |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,ELISA |
Recommended Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/5000. Not yet tested in other applications. |
Concentration | 1 mg/ml |
Reactive Species | Human,Mouse,Rat |
Host Species | Rabbit |
Immunogen | Synthesized peptide derived from Orexin R-1, at AA range: 200-280 |
Specificity | Orexin R-1 Polyclonal Antibody detects endogenous levels of Orexin R-1 protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Gene Name | HCRTR1 |
Accession No. | O43613 P58307 P56718 |
Alternate Names | HCRTR1; Orexin receptor type 1; Ox-1-R; Ox1-R; Ox1R; Hypocretin receptor type 1 |
Description | hypocretin receptor 1(HCRTR1) Homo sapiens The protein encoded by this gene is a G-protein coupled receptor involved in the regulation of feeding behavior. The encoded protein selectively binds the hypothalamic neuropeptide orexin A. A related gene (HCRTR2) encodes a G-protein coupled receptor that binds orexin A and orexin B. [provided by RefSeq, Jan 2009], |
Cell Pathway/ Category | Neuroactive ligand-receptor interaction, |
Protein Expression | Brain, |
Subcellular Localization | plasma membrane,integral component of plasma membrane,integral component of membrane, |
Protein Function | function:Moderately selective excitatory receptor for orexin-A and, with a lower affinity, for orexin-B neuropeptide. Seems to be exclusively coupled to the G(q) subclass of heteromeric G proteins, which activates the phospholipase C mediated signaling cascade.,similarity:Belongs to the G-protein coupled receptor 1 family., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |