ITT3473
ITT3473
- Catalog: ITT3473
- Gene/Protein: OXSR1
- Product Description: Immunotag™ OSR1 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | OSR1 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | IHC-p,ELISA |
| Recommended Dilution | Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse |
| Host Species | Rabbit |
| Immunogen | The antiserum was produced against synthesized peptide derived from human OSR1. AA range:151-200 |
| Specificity | OSR1 Polyclonal Antibody detects endogenous levels of OSR1 protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | OXSR1 |
| Accession No. | O95747 Q6P9R2 |
| Alternate Names | OXSR1; KIAA1101; OSR1; Serine/threonine-protein kinase OSR1; Oxidative stress-responsive 1 protein |
| Description | oxidative stress responsive 1(OXSR1) Homo sapiens The product of this gene belongs to the Ser/Thr protein kinase family of proteins. It regulates downstream kinases in response to environmental stress, and may play a role in regulating the actin cytoskeleton. [provided by RefSeq, Jul 2008], |
| Protein Expression | Brain,Epithelium,Liver,Skeletal muscle, |
| Subcellular Localization | intracellular,cytoplasm,extracellular exosome, |
| Protein Function | catalytic activity:ATP + a protein = ADP + a phosphoprotein.,cofactor:Magnesium.,enzyme regulation:By autophosphorylation on threonine.,function:Regulates downstream kinases in response to environmental stress. May also have a function in regulating the actin cytoskeleton.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.,similarity:Contains 1 protein kinase domain.,subunit:Binds to and phosphorylates PAK1. Interacts with chloride channel proteins SLC12A6 isoform 2, SLC12A1 and SLC12A2 but not with SLC12A4 and SLC12A7, possibly establishing sensor/signaling modules that initiate the cellular response to environmental stress. Binds to and phosphorylates RELL1, RELL2 AND RELT.,tissue specificity:Ubiquitously expressed in all tissue examined., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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