ITT3483
ITT3483
- Catalog: ITT3483
- Gene/Protein: ACRBP
- Product Description: Immunotag™ OY-TES-1 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | OY-TES-1 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,IHC-p,IF,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human |
| Host Species | Rabbit |
| Immunogen | The antiserum was produced against synthesized peptide derived from human ACRBP. AA range:181-230 |
| Specificity | OY-TES-1 Polyclonal Antibody detects endogenous levels of OY-TES-1 protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | ACRBP |
| Accession No. | Q8NEB7 Q3V140 |
| Alternate Names | ACRBP; Acrosin-binding protein; Cancer/testis antigen 23; CT23; Cancer/testis antigen OY-TES-1; Proacrosin-binding protein sp32 |
| Description | acrosin binding protein(ACRBP) Homo sapiens The protein encoded by this gene is similar to proacrosin binding protein sp32 precursor found in mouse, guinea pig, and pig. This protein is located in the sperm acrosome and is thought to function as a binding protein to proacrosin for packaging and condensation of the acrosin zymogen in the acrosomal matrix. This protein is a member of the cancer/testis family of antigens and it is found to be immunogenic. In normal tissues, this mRNA is expressed only in testis, whereas it is detected in a range of different tumor types such as bladder, breast, lung, liver, and colon. [provided by RefSeq, Jul 2008], |
| Protein Expression | Testis, |
| Subcellular Localization | acrosomal vesicle,acrosomal membrane,extracellular region,nucleus, |
| Protein Function | function:May be involved in packaging and condensation of the acrosin zymogen in the acrosomal matrix via its association with proacrosin.,PTM:Phosphorylated on Tyr residues in capacitated sperm.,PTM:The N-terminus is blocked.,subcellular location:Colocalizes with proacrosin in the acrosome of sperm.,subunit:Binds proacrosin.,tissue specificity:Expression restricted to testis in normal tissue. Expressed in a wide spectrum of cancers, including bladder, breast, liver, lung and colon cancers., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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