ITT3491
ITT3491
- Catalog: ITT3491
- Gene/Protein: SRCIN1
- Product Description: Immunotag™ p140Cap Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | p140Cap |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse,Rat |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from p140Cap, at AA range: 780-860 |
| Specificity | p140Cap Polyclonal Antibody detects endogenous levels of p140Cap protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | SRCIN1 |
| Accession No. | Q9C0H9 Q9QWI6 Q9QXY2 |
| Alternate Names | SRCIN1; KIAA1684; P140; SRC kinase signaling inhibitor 1; SNAP-25-interacting protein; SNIP; p130Cas-associated protein; p140Cap |
| Description | function:Delays the onset of cell spreading in the early stages of cell adhesion to fibronectin. Also involved in calcium-dependent exocytosis from PC12 cells.,PTM:Tyrosine-phosphorylated in response to EGF and to cell adhesion to integrin ligands.,similarity:Belongs to the p140Cap family.,subcellular location:Localized to the perinuclear region, lamellopodia, cortical actin and actin stress fibers but not to focal adhesions.,subunit:Interacts with the N-terminal coiled-coil region of SNAP25 (By similarity). Interacts with BCAR1/p130Cas through its C-terminal domain., |
| Protein Expression | Brain,Brain cortex,Cerebellum,Eye, |
| Subcellular Localization | cytoplasm,focal adhesion,postsynaptic density,actin cytoskeleton,lamellipodium,cell junction,filopodium,axon,dendrite,neuronal cell body,synapse,postsynaptic membrane, |
| Protein Function | function:Delays the onset of cell spreading in the early stages of cell adhesion to fibronectin. Also involved in calcium-dependent exocytosis from PC12 cells.,PTM:Tyrosine-phosphorylated in response to EGF and to cell adhesion to integrin ligands.,similarity:Belongs to the p140Cap family.,subcellular location:Localized to the perinuclear region, lamellopodia, cortical actin and actin stress fibers but not to focal adhesions.,subunit:Interacts with the N-terminal coiled-coil region of SNAP25 (By similarity). Interacts with BCAR1/p130Cas through its C-terminal domain., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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