ITT3503
ITT3503
- Catalog: ITT3503
- Gene/Protein: P2RY13
- Product Description: Immunotag™ P2RY13 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | P2RY13 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,IHC-p,IF,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Rat |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from P2RY13, at AA range: 180-260 |
| Specificity | P2RY13 Polyclonal Antibody detects endogenous levels of P2RY13 protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | P2RY13 |
| Accession No. | Q9BPV8 Q9D8I2 Q6GUG4 |
| Alternate Names | P2RY13; GPR86; GPR94; FKSG77; P2Y purinoceptor 13; P2Y13; G-protein coupled receptor 86; G-protein coupled receptor 94 |
| Description | purinergic receptor P2Y13(P2RY13) Homo sapiens The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is activated by ADP. [provided by RefSeq, Sep 2008], |
| Cell Pathway/ Category | Neuroactive ligand-receptor interaction, |
| Protein Expression | Amygdala,Brain,Caudate nucleus,Fetal brain,Heart,Placenta,Spleen, |
| Subcellular Localization | endoplasmic reticulum,plasma membrane,integral component of plasma membrane,integral component of membrane, |
| Protein Function | function:Receptor for ADP. Coupled to G(i)-proteins. May play a role in hematopoiesis and the immune system.,miscellaneous:Stimulation by ADP in stably transfected CHO cells resulted in inhibition of adenylyl cyclase and the phosphorylation of the MAP kinases MAPK3 and MAPK1 in a pertussis toxin-sensitive way. Inhibition of adenylyl cyclase and phosphorylation of the MAP kinases are transduction mechanisms that involve G(i) proteins.,sequence caution:Contaminating sequence. Potential poly-A sequence.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Strong expression in spleen and adult brain. Lower expression in placenta, lung, liver, spinal cord, thymus, small intestine, uterus, stomach, testis, fetal brain, and adrenal gland. Not detected in pancreas, heart, kidney, skeletal muscle, ovary or fetal aorta. Clearly detected in lymph node and bone marrow, weakly detected in peripheral blood mononuclear cells (PBMC) and in peripheral blood leukocytes (PBL), but not detected in polymorphonuclear cells (PMN). In the brain, detected in all brain regions examined., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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