ITT3571
ITT3571
- Catalog: ITT3571
- Gene/Protein: SERPINA5
- Product Description: Immunotag™ PAI-3 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | PAI-3 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,IHC-p,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human |
| Host Species | Rabbit |
| Immunogen | The antiserum was produced against synthesized peptide derived from human Serpin A5. AA range:260-309 |
| Specificity | PAI-3 Polyclonal Antibody detects endogenous levels of PAI-3 protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | SERPINA5 |
| Accession No. | P05154 P70458 |
| Alternate Names | SERPINA5; PCI; PLANH3; Plasma serine protease inhibitor; Acrosomal serine protease inhibitor; Plasminogen activator inhibitor 3; PAI-3; PAI3; Protein C inhibitor; PCI; Serpin A5 |
| Description | serpin family A member 5(SERPINA5) Homo sapiens The protein encoded by this gene is a member of the serpin family of proteins, a group of proteins that inhibit serine proteases. This gene is one in a cluster of serpin genes located on the q arm of chromosome 14. This family member is a glycoprotein that can inhibit several serine proteases, including protein C and various plasminogen activators and kallikreins, and it thus plays diverse roles in hemostasis and thrombosis in multiple organs. [provided by RefSeq, Aug 2012], |
| Cell Pathway/ Category | Complement and coagulation cascades, |
| Protein Expression | Liver,Plasma,Skin,Testis, |
| Subcellular Localization | acrosomal membrane,extracellular region,extracellular space,external side of plasma membrane,membrane,platelet alpha granule,platelet dense tubular network,protein C inhibitor-TMPRSS7 complex,protein C inhibitor-TMPRSS11E complex,protein C in |
| Protein Function | function:Inhibits activated protein C as well as plasminogen activators.,similarity:Belongs to the serpin family.,tissue specificity:Expressed by the liver and secreted in plasma., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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