ITT3702
ITT3702
- Catalog: ITT3702
- Gene/Protein: PHKG1
- Product Description: Immunotag™ PHKG1 Polyclonal Antibody
385.0000
Price in reward points: 385
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Antibody Specification | |
Datasheet | |
Target Protein | PHKG1 |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,ELISA |
Recommended Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications. |
Concentration | 1 mg/ml |
Reactive Species | Human |
Host Species | Rabbit |
Immunogen | The antiserum was produced against synthesized peptide derived from human PHKG1. AA range:241-290 |
Specificity | PHKG1 Polyclonal Antibody detects endogenous levels of PHKG1 protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Gene Name | PHKG1 |
Accession No. | Q16816 P07934 |
Alternate Names | PHKG1; PHKG; Phosphorylase b kinase gamma catalytic chain; skeletal muscle isoform; Phosphorylase kinase subunit gamma-1 |
Description | phosphorylase kinase catalytic subunit gamma 1(PHKG1) Homo sapiens This gene is a member of the Ser/Thr protein kinase family and encodes a protein with one protein kinase domain and two calmodulin-binding domains. This protein is the catalytic member of a 16 subunit protein kinase complex which contains equimolar ratios of 4 subunit types. The complex is a crucial glycogenolytic regulatory enzyme. This gene has two pseudogenes at chromosome 7q11.21 and one at chromosome 11p11.12. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2012], |
Cell Pathway/ Category | Calcium,Insulin_Receptor, |
Protein Expression | PCR rescued clones,Salivary gland,Skeletal muscle, |
Subcellular Localization | cytosol,phosphorylase kinase complex, |
Protein Function | catalytic activity:2 ATP + phosphorylase b = 2 ADP + phosphorylase a.,domain:The two calmodulin-binding domains appear to act in concert to bind a single molecule of calmodulin and are pseudosubstrate/autoinhibitory domains.,function:Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I.,similarity:Belongs to the protein kinase superfamily.,similarity:Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.,similarity:Contains 1 protein kinase domain.,subunit:Polymer of 16 chains, four each of alpha, beta, gamma, and delta. Alpha and beta are regulatory chains, gamma is the catalytic chain, and delta is calmodulin., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |