ITT3725
ITT3725
- Catalog: ITT3725
- Gene/Protein: PIGH
- Product Description: Immunotag™ PIG-H Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | PIG-H |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | IHC-p,ELISA |
| Recommended Dilution | Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse |
| Host Species | Rabbit |
| Immunogen | The antiserum was produced against synthesized peptide derived from human PIGH. AA range:137-186 |
| Specificity | PIG-H Polyclonal Antibody detects endogenous levels of PIG-H protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | PIGH |
| Accession No. | Q14442 Q5M9N4 |
| Alternate Names | PIGH; Phosphatidylinositol N-acetylglucosaminyltransferase subunit H; Phosphatidylinositol-glycan biosynthesis class H protein; PIG-H |
| Description | phosphatidylinositol glycan anchor biosynthesis class H(PIGH) Homo sapiens This gene encodes an endoplasmic reticulum associated protein that is involved in glycosylphosphatidylinositol (GPI)-anchor biosynthesis. The GPI anchor is a glycolipid found on many blood cells and which serves to anchor proteins to the cell surface. The protein encoded by this gene is a subunit of the GPI N-acetylglucosaminyl (GlcNAc) transferase that transfers GlcNAc to phosphatidylinositol (PI) on the cytoplasmic side of the endoplasmic reticulum. [provided by RefSeq, Jul 2008], |
| Cell Pathway/ Category | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis, |
| Protein Expression | Blood,Lung,Placenta, |
| Subcellular Localization | glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex,endoplasmic reticulum,endoplasmic reticulum membrane,integral component of membrane, |
| Protein Function | catalytic activity:UDP-N-acetyl-D-glucosamine + 1-phosphatidyl-1D-myo-inositol = UDP + 6-(N-acetyl-alpha-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol.,function:Part of the complex catalyzing the transfer of N-acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol, the first step of GPI biosynthesis.,online information:Phosphatidylinositol N-acetylglucosaminyltransferase subunit H,pathway:Glycolipid biosynthesis; glycosylphosphatidylinositol-anchor biosynthesis.,similarity:Belongs to the PIGH family.,subunit:Associates with PIGA, PIGC, PIGP, PIGQ and DPM2. The latter is not essential for activity., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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