ITT3812
ITT3812
- Catalog: ITT3812
- Gene/Protein: POLR2J
- Product Description: Immunotag™ POLR2J1 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | POLR2J1 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse |
| Host Species | Rabbit |
| Immunogen | The antiserum was produced against synthesized peptide derived from human RPB11. AA range:10-59 |
| Specificity | POLR2J1 Polyclonal Antibody detects endogenous levels of POLR2J1 protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | POLR2J |
| Accession No. | P52435 O08740 |
| Alternate Names | POLR2J; POLR2J1; DNA-directed RNA polymerase II subunit RPB11-a; RNA polymerase II subunit B11-a; RPB11a; DNA-directed RNA polymerase II subunit J-1; RNA polymerase II 13.3 kDa subunit |
| Description | RNA polymerase II subunit J(POLR2J) Homo sapiens This gene encodes a subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene exists as a heterodimer with another polymerase subunit; together they form a core subassembly unit of the polymerase. Two similar genes are located nearby on chromosome 7q22.1 and a pseudogene is found on chromosome 7p13. [provided by RefSeq, Jul 2008], |
| Cell Pathway/ Category | Purine metabolism,Pyrimidine metabolism,RNA polymerase,Huntington's disease, |
| Protein Expression | Bone marrow,Colon,Embryonic kidney,Kidney,Placenta, |
| Subcellular Localization | nucleus,nucleoplasm,DNA-directed RNA polymerase II, core complex, |
| Protein Function | function:DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB11 is part of the core element with the central large cleft.,similarity:Belongs to the archaeal rpoL/eukaryotic RPB11/RPC19 RNA polymerase subunit family.,subunit:Component of the RNA polymerase II (Pol II) complex consisting of 12 subunits. Interacts with AATF.,tissue specificity:Ubiquitously expressed. High expression was found in heart and skeletal muscle., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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