ITT3837
ITT3837
- Catalog: ITT3837
- Gene/Protein: PPP1R14D
- Product Description: Immunotag™ PPP1R14D Polyclonal Antibody
385.0000
Price in reward points: 385
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Antibody Specification | |
Datasheet | |
Target Protein | PPP1R14D |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,IHC-p,ELISA |
Recommended Dilution | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications. |
Concentration | 1 mg/ml |
Reactive Species | Human |
Host Species | Rabbit |
Immunogen | The antiserum was produced against synthesized peptide derived from human PPP1R14D. AA range:66-115 |
Specificity | PPP1R14D Polyclonal Antibody detects endogenous levels of PPP1R14D protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Gene Name | PPP1R14D |
Accession No. | Q9NXH3 Q7TT52 |
Alternate Names | PPP1R14D; GBPI; Protein phosphatase 1 regulatory subunit 14D; Gastrointestinal and brain-specific PP1-inhibitory protein 1; GBPI-1 |
Description | protein phosphatase 1 regulatory inhibitor subunit 14D(PPP1R14D) Homo sapiens Protein phosphatase-1 (PP1; see MIM 176875) is a major cellular phosphatase that reverses serine/threonine protein phosphorylation. PPP1R14D is a PP1 inhibitor that itself is regulated by phosphorylation (Liu et al., 2004 [PubMed 12974676]).[supplied by OMIM, Feb 2010], |
Protein Expression | Colon mucosa,PCR rescued clones, |
Subcellular Localization | cytoplasm, |
Protein Function | function:Inhibitor of PPP1CA. Has inhibitory activity only when phosphorylated, creating a molecular switch for regulating the phosphorylation status of PPP1CA substrates and smooth muscle contraction.,PTM:Phosphorylated on several residues.,similarity:Belongs to the PP1 inhibitor family.,tissue specificity:Detected in colon, intestine, kidney and brain cortex., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |