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ITT3841

ITT3841
ITT3841
ITT3841
  • Gene/Protein: PPP2R3C
  • Product Description: Immunotag™ PPP2R3C Polyclonal Antibody
280.0000
Price in reward points: 294

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Immunotag™ PPP2R3C Polyclonal Antibody
Antibody Specification
Datasheet
Target Protein PPP2R3C
Clonality Polyclonal
Storage/Stability -20°C/1 year
Application WB,ELISA
Recommended Dilution Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
Concentration 1 mg/ml
Reactive Species Human,Mouse,Rat
Host Species Rabbit
Immunogen Synthesized peptide derived from PPP2R3C, at AA range: 140-220
Specificity PPP2R3C Polyclonal Antibody detects endogenous levels of PPP2R3C protein.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Gene Name PPP2R3C
Accession No. Q969Q6 Q9JK24 Q6AXZ3
Alternate Names PPP2R3C; C14orf10; G5PR; Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma; Protein phosphatase subunit G5PR; Rhabdomyosarcoma antigen MU-RMS-40.6A/6C
Description protein phosphatase 2 regulatory subunit B''gamma(PPP2R3C) Homo sapiens This gene encodes a regulatory subunit of the serine/threonine phosphatase, protein phosphatase 2. This protein is localized to both nuclear and cytoplasmic regions depending on cell cycle phase. Homozygous conditional knockout mice for this gene exhibit reduced numbers and impaired proliferation of immune system B cells. This protein may regulate the expression of the P-glycoprotein ATP-binding cassette transporter through its phosphatase activity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2015],
Protein Expression Bone marrow,Brain,Embryonic rhabdomyosarcoma,Gastri
Subcellular Localization nucleus,cytoplasm,centrosome,spindle,
Protein Function developmental stage:Expressed in fetal brain.,function:May regulate MCM3AP phosphorylation through phosphatase recruitment. May play a role in the activation-induced cell death of B-cells.,similarity:Contains 2 EF-hand domains.,subcellular location:Excluded from the nucleoli. Localization is cell cycle-dependent. Localizes to the cytoplasm during cytokinesis.,subunit:Interacts with MCM3AP/GANP (By similarity). Interacts with PPP5C, and the phosphatase 2A core enzyme composed of the PPP2CA catalytic subunit and the constant regulatory subunit PPP2R1A.,tissue specificity:Ubiquitously expressed in brain and other tissues.,
Usage For Research Use Only! Not for diagnostic or therapeutic procedures.
Material Safety Data Sheet
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