ITT3858
ITT3858
- Catalog: ITT3858
- Gene/Protein: PRIM1
- Product Description: Immunotag™ PRIM1 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
|
| Target Protein | PRIM1 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,IHC-p,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse,Rat |
| Host Species | Rabbit |
| Immunogen | The antiserum was produced against synthesized peptide derived from human PRIM1. AA range:371-420 |
| Specificity | PRIM1 Polyclonal Antibody detects endogenous levels of PRIM1 protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | PRIM1 |
| Accession No. | P49642 P20664 |
| Alternate Names | PRIM1; DNA primase small subunit; DNA primase 49 kDa subunit; p49 |
| Description | primase (DNA) subunit 1(PRIM1) Homo sapiens The replication of DNA in eukaryotic cells is carried out by a complex chromosomal replication apparatus, in which DNA polymerase alpha and primase are two key enzymatic components. Primase, which is a heterodimer of a small subunit and a large subunit, synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication. The protein encoded by this gene is the small, 49 kDa primase subunit. [provided by RefSeq, Jul 2008], |
| Cell Pathway/ Category | Purine metabolism,Pyrimidine metabolism,DNA replication, |
| Protein Expression | Bone marrow,Thymus, |
| Subcellular Localization | nucleoplasm,alpha DNA polymerase:primase complex,membrane,primosome complex, |
| Protein Function | function:DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication.,miscellaneous:The bound zinc ion is not a cofactor. It is bound to a zinc knuckle motif that may be involved in sequence recognition and the binding of ssDNA.,similarity:Belongs to the eukaryotic-type primase small subunit family.,subunit:Heterodimer of a small subunit and a large subunit., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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