ITT3859
ITT3859
- Catalog: ITT3859
- Gene/Protein: PRKX
- Product Description: Immunotag™ PRKX Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | PRKX |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,IHC-p,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse,Rat |
| Host Species | Rabbit |
| Immunogen | The antiserum was produced against synthesized peptide derived from human PRKX. AA range:251-300 |
| Specificity | PRKX Polyclonal Antibody detects endogenous levels of PRKX protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | PRKX |
| Accession No. | P51817 Q922R0 |
| Alternate Names | PRKX; PKX1; cAMP-dependent protein kinase catalytic subunit PRKX; PrKX; Protein kinase X; Protein kinase X-linked; Serine/threonine-protein kinase PRKX; Protein kinase PKX1 |
| Description | protein kinase, X-linked(PRKX) Homo sapiens This gene encodes a serine threonine protein kinase that has similarity to the catalytic subunit of cyclic AMP dependent protein kinases. The encoded protein is developmentally regulated and may be involved in renal epithelial morphogenesis. This protein may also be involved in macrophage and granulocyte maturation. Abnormal recombination between this gene and a related pseudogene on chromosome Y is a frequent cause of sex reversal disorder in XX males and XY females. Pseudogenes of this gene are found on chromosomes X, 15 and Y. [provided by RefSeq, Feb 2010], |
| Cell Pathway/ Category | MAPK_ERK_Growth,MAPK_G_Protein,Calcium,Chemokine,Oocyte meiosis,Apoptosis_Inhibition,Apoptosis_Mitochondrial,Apoptosis_Overview,Vascular smooth muscle contraction,WNT,WNT-T CELLHedgehog,Gap junction,Long-term potentiation,Olfactory transduction,Taste transduction,Insulin_Receptor,GnRH,Progesterone-mediated oocyte maturation,Melanogenesis,Prion diseases,Vibrio cholerae infection,Dilated cardiomyopathy, |
| Protein Expression | Blood,Fetal brain, |
| Subcellular Localization | nucleus,cytoplasm, |
| Protein Function | catalytic activity:ATP + a protein = ADP + a phosphoprotein.,disease:A chromosomal aberration involving PRKX is a cause of sex reversal disorder. Translocation t(X;Y)(p22;p11) with PRKY. Chromosomal translocations proximal to PRKY account for about 30% of the cases of sex reversal disorder in XX males and XY females.,similarity:Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cAMP subfamily.,similarity:Contains 1 AGC-kinase C-terminal domain.,similarity:Contains 1 protein kinase domain.,tissue specificity:High levels in adult and fetal brain, kidney and lung; low levels in adult placenta, heart, liver, skeletal muscle, pancreas and fetal liver., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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