ITT3865
ITT3865
- Catalog: ITT3865
- Gene/Protein: PRPF6
- Product Description: Immunotag™ PRP6 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | PRP6 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | IHC-p,WB,ELISA |
| Recommended Dilution | WB 1:500-2000 Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse,Rat |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from PRP6, at AA range: 720-800 |
| Specificity | PRP6 Polyclonal Antibody detects endogenous levels of PRP6 protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | PRPF6 |
| Accession No. | O94906 Q91YR7 A1A5S1 |
| Alternate Names | PRPF6; C20orf14; Pre-mRNA-processing factor 6; Androgen receptor N-terminal domain-transactivating protein 1; ANT-1; PRP6 homolog; U5 snRNP-associated 102 kDa protein; U5-102 kDa protein |
| Description | pre-mRNA processing factor 6(PRPF6) Homo sapiens The protein encoded by this gene appears to be involved in pre-mRNA splicing, possibly acting as a bridging factor between U5 and U4/U6 snRNPs in formation of the spliceosome. The encoded protein also can bind androgen receptor, providing a link between transcriptional activation and splicing. [provided by RefSeq, Jul 2008], |
| Cell Pathway/ Category | Spliceosome, |
| Protein Expression | Cervix carcinoma,Colon,Testis, |
| Subcellular Localization | nucleus,nucleoplasm,spliceosomal complex,U5 snRNP,membrane,nuclear speck,U4/U6 x U5 tri-snRNP complex,catalytic step 2 spliceosome, |
| Protein Function | function:Involved in pre-mRNA splicing. May act in the tri-snRNP complex as a bridging factor between U5 and U4/U6 snRNPs in the late step of spliceosome assembly. May be necessary for tri-snRNP formation.,similarity:Contains 9 HAT repeats.,subunit:Associates with the U5 snRNP particle (containing the 40 kDa, 52 kDa, 116 kDa, 200 kDa and 220 kDa proteins) probably via interaction(s) with the 220 kDa and/or other proteins. Associates with U4/U6 snRNP particle (containing the 15.5 kDa, 20 kDa/60kDa/90kDa heteromer, LSm proteins LSm2-8, 61 kDa and Sm proteins). Interacts with ARAF1. Identified in the spliceosome C complex, at least composed of AQR, ASCC3L1, C19orf29, CDC40, CDC5L, CRNKL1, DDX23, DDX41, DDX48, DDX5, DGCR14, DHX35, DHX38, DHX8, EFTUD2, FRG1, GPATC1, HNRPA1, HNRPA2B1, HNRPA3, HNRPC, HNRPF, HNRPH1, HNRPK, HNRPM, HNRPR, HNRPU, KIAA1160, KIAA1604, LSM2, LSM3, MAGOH, MORG1, PABPC1, PLRG1, PNN, PPIE, PPIL1, PPIL3, PPWD1, PRPF19, PRPF4B, PRPF6, PRPF8, RALY, RBM22, RBM8A, RBMX, SART1, SF3A1, SF3A2, SF3A3, SF3B1, SF3B2, SF3B3, SFRS1, SKIV2L2, SNRPA1, SNRPB, SNRPB2, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF, SNRPG, SNW1, SRRM1, SRRM2, SYF2, SYNCRIP, TFIP11, THOC4, U2AF1, WDR57, XAB2 and ZCCHC8., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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