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ITT3874

ITT3874-2
ITT3874
ITT3874-2
ITT3874
ITT3874
  • Catalog: ITT3874
  • Gene/Protein: PRRX1
  • Product Description: Immunotag™ PRX1 Polyclonal Antibody
385.0000
Price in reward points: 385

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Immunotag™ PRX1 Polyclonal Antibody
Antibody Specification
Datasheet
Target Protein PRX1
Clonality Polyclonal
Storage/Stability -20°C/1 year
Application WB,ELISA
Recommended Dilution Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Concentration 1 mg/ml
Reactive Species Human,Mouse,Rat
Host Species Rabbit
Immunogen Synthesized peptide derived from PRX1, at AA range: 30-110
Specificity PRX1 Polyclonal Antibody detects endogenous levels of PRX1 protein.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Gene Name PRRX1
Accession No. P54821 P63013 P63014
Alternate Names PRRX1; PMX1; Paired mesoderm homeobox protein 1; Homeobox protein PHOX1; Paired-related homeobox protein 1; PRX-1
Description paired related homeobox 1(PRRX1) Homo sapiens The DNA-associated protein encoded by this gene is a member of the paired family of homeobox proteins localized to the nucleus. The protein functions as a transcription co-activator, enhancing the DNA-binding activity of serum response factor, a protein required for the induction of genes by growth and differentiation factors. The protein regulates muscle creatine kinase, indicating a role in the establishment of diverse mesodermal muscle types. Alternative splicing yields two isoforms that differ in abundance and expression patterns. [provided by RefSeq, Jul 2008],
Subcellular Localization nucleus,nucleolus,
Protein Function function:Acts as a transcriptional regulator of muscle creatine kinase (MCK) and so has a role in the establishment of diverse mesodermal muscle types. The protein binds to an A/T-rich element in the muscle creatine enhancer.,similarity:Belongs to the paired homeobox family.,similarity:Contains 1 homeobox DNA-binding domain.,similarity:Contains 1 OAR domain.,
Usage For Research Use Only! Not for diagnostic or therapeutic procedures.
Material Safety Data Sheet
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