ITT3903
ITT3903
- Catalog: ITT3903
- Gene/Protein: PTPRZ1
- Product Description: Immunotag™ PTPζ Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | PTPζ |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/5000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse,Rat |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from PTPζ, at AA range: 100-180 |
| Specificity | PTPζ Polyclonal Antibody detects endogenous levels of PTPζ protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | PTPRZ1 |
| Accession No. | P23471 Q62656 |
| Alternate Names | PTPRZ1; HTPZP2; PTPRZ; PTPRZ2; PTPZ; Receptor-type tyrosine-protein phosphatase zeta; R-PTP-zeta; Protein-tyrosine phosphatase receptor type Z polypeptide 1; Protein-tyrosine phosphatase receptor type Z polypeptide 2; R-PTP-zeta-2 |
| Description | protein tyrosine phosphatase, receptor type Z1(PTPRZ1) Homo sapiens This gene encodes a member of the receptor protein tyrosine phosphatase family. Expression of this gene is restricted to the central nervous system (CNS), and it may be involved in the regulation of specific developmental processes in the CNS. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, May 2011], |
| Cell Pathway/ Category | Epithelial cell signaling in Helicobacter pylori infection, |
| Protein Expression | Brain,Brain stem,Liver,Plasma, |
| Subcellular Localization | proteinaceous extracellular matrix,integral component of plasma membrane,integral component of membrane,intrinsic component of plasma membrane,perineuronal net, |
| Protein Function | catalytic activity:Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate.,caution:PubMed:8387522 and PubMed:2170109 have termed this protein RPTPase beta.,function:May be involved in the regulation of specific developmental processes in the CNS.,sequence caution:Contaminating sequence. The N-terminus may be contaminated with vector sequence.,similarity:Belongs to the protein-tyrosine phosphatase family. Receptor class 5 subfamily.,similarity:Contains 1 alpha-carbonic anhydrase domain.,similarity:Contains 1 fibronectin type-III domain.,similarity:Contains 2 tyrosine-protein phosphatase domains.,subunit:The carbonic-anhydrase like domain binds to contactin.,tissue specificity:Specifically expressed in the central nervous system, where it is localized in the Purkinje cell layer of the cerebellum, the dentate gyrus, and the subependymal layer of the anterior horn of the lateral ventricle. Developmentally regulated in the brain., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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