ITT3921
ITT3921
- Catalog: ITT3921
- Gene/Protein: RAB1B
- Product Description: Immunotag™ Rab 1B Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
|
| Target Protein | Rab 1B |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse,Rat |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from Rab 1B, at AA range: 50-130 |
| Specificity | Rab 1B Polyclonal Antibody detects endogenous levels of Rab 1B protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | RAB1B |
| Accession No. | Q9H0U4 Q9D1G1 P10536 |
| Alternate Names | RAB1B; Ras-related protein Rab-1B |
| Description | RAB1B, member RAS oncogene family(RAB1B) Homo sapiens Members of the RAB protein family, such as RAB1B, are low molecular mass monomeric GTPases localized on the cytoplasmic surfaces of distinct membrane-bound organelles. RAB1B functions in the early secretory pathway and is essential for vesicle transport between the endoplasmic reticulum (ER) and Golgi (Chen et al., 1997 [PubMed 9030196]; Alvarez et al., 2003 [PubMed 12802079]).[supplied by OMIM, Jan 2009], |
| Protein Expression | B-cell lymphoma,Brain,Muscle,Pancreas, |
| Subcellular Localization | Golgi membrane,intracellular,mitochondrion,endoplasmic reticulum membrane,Golgi apparatus,transport vesicle,endoplasmic reticulum-Golgi intermediate compartment membrane,pre-autophagosomal structure membrane,extracellular exosome, |
| Protein Function | function:Protein transport. Regulates vesicular transport between the endoplasmic reticulum and successive Golgi compartments.,miscellaneous:Rab-1B binds GTP and GDP and possesses intrinsic GTPase activity.,PTM:Prenylated; by GGTase II, only after interaction of the substrate with Rab escort protein 1 (REP1).,similarity:Belongs to the small GTPase superfamily. Rab family.,subcellular location:Targeted by REP1 to membranes of specific subcellular compartments including endoplasmic reticulum, Golgi apparatus, and intermediate vesicles between these two compartments. In the GDP-form, colocalizes with GDI in the cytoplasm.,subunit:Interacts with MICAL1, MICAL2 and MICAL3. Interacts with GDI1; the interaction requires the GDP-bound state. Interacts with CHM/REP1; the interaction requires the GDP-bound form and is necessary for prenylation by GGTase II., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
| English_US |
|
| Danish |
|
| Dutch |
|
| English_UK |
|
| French |
|
| German |
|
| Spanish |
|
| Norwegian |
|
| Portuguese |
|
| Finnish |
|
| Swedish |
|
| Polish |
|