ITT3923
ITT3923
- Catalog: ITT3923
- Gene/Protein: RAB24
- Product Description: Immunotag™ Rab 24 Polyclonal Antibody
385.0000
Price in reward points: 385
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Antibody Specification | |
Datasheet | |
Target Protein | Rab 24 |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | IHC-p,ELISA |
Recommended Dilution | Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications. |
Concentration | 1 mg/ml |
Reactive Species | Human,Mouse,Rat |
Host Species | Rabbit |
Immunogen | Synthesized peptide derived from Rab 24 . at AA range: 90-170 |
Specificity | Rab 24 Polyclonal Antibody detects endogenous levels of Rab 24 protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Gene Name | RAB24 |
Accession No. | Q969Q5 P35290 |
Alternate Names | RAB24; Ras-related protein Rab-24 |
Description | RAB24, member RAS oncogene family(RAB24) Homo sapiens RAB24 is a small GTPase of the Rab subfamily of Ras-related proteins that regulate intracellular protein trafficking (Olkkonen et al., 1993 [PubMed 8126105]).[supplied by OMIM, Aug 2009], |
Protein Expression | Amygdala,Pancreas,Skin,Uterus,Whole embryo, |
Subcellular Localization | intracellular,mitochondrion,autophagosome,cytosol,membrane, |
Protein Function | function:May be involved in autophagy-related processes.,induction:By extensive retinoic acid treatment, in Ntera-2 teratoma cell line induced to differentiate into post-mitotic neurons (NTN2) (at protein level).,miscellaneous:The unusual Ser-67, instead of a conserved Gln in other family members, is the cause of low GTPase activity. As a result, the predominant nucleotide associated with the protein is GTP.,PTM:Isoprenylation is inefficient compared to other Rab family members.,similarity:Belongs to the small GTPase superfamily. Rab family.,subcellular location:Only about 20-25% is recovered in the particulate fraction.,subunit:Unlike other Rab family members, does not interact with GDP dissociation inhibitors (GDIs), including ARHGDIA and ARHGDIB., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |