ITT3943
ITT3943
- Catalog: ITT3943
- Gene/Protein: RAB11FIP2
- Product Description: Immunotag™ Rab11-FIP2 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | Rab11-FIP2 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse |
| Host Species | Rabbit |
| Immunogen | The antiserum was produced against synthesized peptide derived from human RAB11FIP2. AA range:340-389 |
| Specificity | Rab11-FIP2 Polyclonal Antibody detects endogenous levels of Rab11-FIP2 protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | RAB11FIP2 |
| Accession No. | Q7L804 |
| Alternate Names | RAB11FIP2; KIAA0941; Rab11 family-interacting protein 2; Rab11-FIP2; NRip11 |
| Description | function:A Rab11 effector protein acting in the regulation of the transport of vesicles from the endosomal recycling compartment (ERC) to the plasma membrane. Also involved in receptor-mediated endocytosis and membrane trafficking of recycling endosomes, probably originating from clathrin-coated vesicles. Binds preferentially to phosphatidylinositol 3,4,5-trisphosphate (PtdInsP3) and phosphatidic acid (PA).,similarity:Contains 1 C2 domain.,subcellular location:Translocates with RAB11A from the vesicles of the endocytic recycling compartment (ERC) to the plasma membrane.,subunit:Homooligomerizes in a Rab11-independent manner. Forms an heterooligomeric complex with RAB11FIP4. Interacts with AP2A1, MYO5B, RAB11A, RAB11B, RAB25 and REPS1. Interacts with RAB11A/RAB11B that has been activated by GTP binding., |
| Cell Pathway/ Category | Endocytosis, |
| Protein Expression | Brain, |
| Subcellular Localization | nucleoplasm,endosome,plasma membrane,cytoplasmic vesicle membrane,intracellular membrane-bounded organelle,recycling endosome membrane, |
| Protein Function | function:A Rab11 effector protein acting in the regulation of the transport of vesicles from the endosomal recycling compartment (ERC) to the plasma membrane. Also involved in receptor-mediated endocytosis and membrane trafficking of recycling endosomes, probably originating from clathrin-coated vesicles. Binds preferentially to phosphatidylinositol 3,4,5-trisphosphate (PtdInsP3) and phosphatidic acid (PA).,similarity:Contains 1 C2 domain.,subcellular location:Translocates with RAB11A from the vesicles of the endocytic recycling compartment (ERC) to the plasma membrane.,subunit:Homooligomerizes in a Rab11-independent manner. Forms an heterooligomeric complex with RAB11FIP4. Interacts with AP2A1, MYO5B, RAB11A, RAB11B, RAB25 and REPS1. Interacts with RAB11A/RAB11B that has been activated by GTP binding., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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