ITT3945
ITT3945
- Catalog: ITT3945
- Gene/Protein: RAB11FIP4
- Product Description: Immunotag™ Rab11-FIP4 Polyclonal Antibody
385.0000
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Antibody Specification | |
Datasheet | |
Target Protein | Rab11-FIP4 |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,IHC-p,ELISA |
Recommended Dilution | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications. |
Concentration | 1 mg/ml |
Reactive Species | Human,Mouse |
Host Species | Rabbit |
Immunogen | The antiserum was produced against synthesized peptide derived from human RAB11FIP4. AA range:452-501 |
Specificity | Rab11-FIP4 Polyclonal Antibody detects endogenous levels of Rab11-FIP4 protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Gene Name | RAB11FIP4 |
Accession No. | Q86YS3 Q8BQP8 |
Alternate Names | RAB11FIP4; ARFO2; KIAA1821; Rab11 family-interacting protein 4; FIP4-Rab11; Rab11-FIP4; Arfophilin-2 |
Description | RAB11 family interacting protein 4(RAB11FIP4) Homo sapiens Proteins of the large Rab GTPase family (see RAB1A; MIM 179508) have regulatory roles in the formation, targeting, and fusion of intracellular transport vesicles. RAB11FIP4 is one of many proteins that interact with and regulate Rab GTPases (Hales et al., 2001 [PubMed 11495908]).[supplied by OMIM, Apr 2008], |
Cell Pathway/ Category | Endocytosis, |
Protein Expression | Brain,Spleen,Testis, |
Subcellular Localization | extracellular space,endosome,microtubule organizing center,spindle,endocytic vesicle,midbody,cleavage furrow,perinuclear region of cytoplasm,recycling endosome membrane, |
Protein Function | function:A Rab11 effector protein acting in the endosomal trafficking.,similarity:Contains 1 EF-hand domain.,subcellular location:Colocalizes with RAB11A in the endocytic recycling compartment (ERC).,subunit:Homooligomer. Forms an heterooligomeric complex with RAB11FIP2, RAB11FIP3 and RAB11FIP5. Interacts with RAB11A that has been activated by GTP binding., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |