ITT4079
ITT4079
- Catalog: ITT4079
- Gene/Protein: RHOD
- Product Description: Immunotag™ Rho D Polyclonal Antibody
385.0000
Price in reward points: 385
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Antibody Specification | |
Datasheet | |
Target Protein | RHO D |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,ELISA |
Recommended Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications. |
Concentration | 1 mg/ml |
Reactive Species | Human |
Host Species | Rabbit |
Immunogen | The antiserum was produced against synthesized peptide derived from human RHOD. AA range:113-162 |
Specificity | Rho D Polyclonal Antibody detects endogenous levels of Rho D protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Gene Name | RHOD |
Accession No. | O00212 P97348 |
Alternate Names | RHOD; ARHD; Rho-related GTP-binding protein RhoD; Rho-related protein HP1; RhoHP1 |
Description | ras homolog family member D(RHOD) Homo sapiens Ras homolog, or Rho, proteins interact with protein kinases and may serve as targets for activated GTPase. They play a critical role in muscle differentiation. The protein encoded by this gene binds GTP and is a member of the small GTPase superfamily. It is involved in endosome dynamics and reorganization of the actin cytoskeleton, and it may coordinate membrane transport with the function of the cytoskeleton. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014], |
Cell Pathway/ Category | Axon guidance, |
Protein Expression | Cervix,Placenta, |
Subcellular Localization | intracellular,early endosome,cytosol,plasma membrane,endosome membrane, |
Protein Function | function:Involved in endosome dynamics. May coordinate membrane transport with the function of the cytoskeleton. Participates in reorganization of actin cytoskeleton.,similarity:Belongs to the small GTPase superfamily. Rho family.,subunit:In the GTP-bound form, interacts with DIAPH2 isoform 3.,tissue specificity:Heart, placenta, liver, skeletal muscle, and pancreas and, with weaker intensity, in several other tissues., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |