ITT4080
ITT4080
- Catalog: ITT4080
- Gene/Protein: RHOG
- Product Description: Immunotag™ Rho G Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | RHO G |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,IHC-p,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse,Rat |
| Host Species | Rabbit |
| Immunogen | The antiserum was produced against synthesized peptide derived from human RHOG. AA range:97-146 |
| Specificity | Rho G Polyclonal Antibody detects endogenous levels of Rho G protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | RHOG |
| Accession No. | P84095 P84096 |
| Alternate Names | RHOG; ARHG; Rho-related GTP-binding protein RhoG |
| Description | ras homolog family member G(RHOG) Homo sapiens This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. The encoded protein facilitates translocation of a functional guanine nucleotide exchange factor (GEF) complex from the cytoplasm to the plasma membrane where ras-related C3 botulinum toxin substrate 1 is activated to promote lamellipodium formation and cell migration. Two related pseudogene have been identified on chromosomes 20 and X. [provided by RefSeq, Aug 2011], |
| Protein Expression | Brain,PCR rescued clones, |
| Subcellular Localization | intracellular,endoplasmic reticulum membrane,cytosol,plasma membrane,focal adhesion,extracellular exosome, |
| Protein Function | function:Required for the formation of membrane ruffles during macropinocytosis. Required for the formation of cup-like structures during trans-endothelial migration of leukocytes. In case of Salmonella enterica infection, activated by SopB and SGEF, which induces cytoskeleton rearrangements and promotes bacterial entry.,similarity:Belongs to the small GTPase superfamily. Rho family.,subunit:Interacts with SGEF., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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