ITT4151
ITT4151
- Catalog: ITT4151
- Gene/Protein: URI1
- Product Description: Immunotag™ RMP Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | RMP |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,IHC-p,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human |
| Host Species | Rabbit |
| Immunogen | The antiserum was produced against synthesized peptide derived from human RMP. AA range:415-464 |
| Specificity | RMP Polyclonal Antibody detects endogenous levels of RMP protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | URI1 |
| Accession No. | O94763 Q3TLD5 |
| Alternate Names | URI1; C19orf2; NNX3; PPP1R19; RMP; URI; Unconventional prefoldin RPB5 interactor 1; Protein NNX3; Protein phosphatase 1 regulatory subunit 19; RNA polymerase II subunit 5-mediating protein; RPB5-mediating protein |
| Description | URI1, prefoldin like chaperone(URI1) Homo sapiens This gene encodes member of the prefoldin family of molecular chaperones. The encoded protein functions as a scaffolding protein and plays roles in ubiquitination and transcription, in part though interactions with the RNA polymerase II subunit RPB5. This gene may play a role in multiple malignancies including ovarian cancer and hepatocellular carcinoma. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 22. [provided by RefSeq, Nov 2011], |
| Protein Expression | Epithelium,Hepatoma,Skin,Testis,Uterus, |
| Subcellular Localization | nucleus,DNA-directed RNA polymerase II, core complex,cytoplasm,mitochondrion,dendrite,intracellular membrane-bounded organelle, |
| Protein Function | function:Seems to be a scaffolding protein able to assemble a prefoldin-like complex that contains PFDs and proteins with roles in transcription and ubiquitination.,similarity:Belongs to the RNA polymerase II subunit 5-mediating protein family.,subunit:Component of the URI complex that contains PFD2, POLR2E/RPB5, TIP48, TIP49 and URI. Interacts with POLR2E/RPB5 and LRPPRC.,tissue specificity:Ubiquitous., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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