ITT4203
ITT4203
- Catalog: ITT4203
- Gene/Protein: S100P
- Product Description: Immunotag™ S-100P Polyclonal Antibody
385.0000
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Antibody Specification | |
Datasheet | |
Target Protein | S-100P |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,IHC-p,ELISA |
Recommended Dilution | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications. |
Concentration | 1 mg/ml |
Reactive Species | Human |
Host Species | Rabbit |
Immunogen | The antiserum was produced against synthesized peptide derived from human S100P. AA range:26-75 |
Specificity | S-100P Polyclonal Antibody detects endogenous levels of S-100P protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Gene Name | S100P |
Accession No. | P25815 |
Alternate Names | S100P; S100E; Protein S100-P; Protein S100-E; S100 calcium-binding protein P |
Description | S100 calcium binding protein P(S100P) Homo sapiens The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21; however, this gene is located at 4p16. This protein, in addition to binding Ca2+, also binds Zn2+ and Mg2+. This protein may play a role in the etiology of prostate cancer. [provided by RefSeq, Jul 2008], |
Protein Expression | Placenta, |
Subcellular Localization | nucleus,cytoplasm,cell-cell adherens junction,microvillus membrane,extracellular exosome, |
Protein Function | miscellaneous:This protein binds two calcium ions.,similarity:Belongs to the S-100 family.,similarity:Contains 2 EF-hand domains.,subcellular location:Colocalizes with S100PBP in the nucleus.,subunit:Homodimer. Interacts with S100PBP and S100Z.,tissue specificity:Up-regulated in various pancreatic ductal adenocarcinomas and pancreatic intraepithelial neoplasias., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |