ITT4239
ITT4239
- Catalog: ITT4239
- Gene/Protein: SENP5
- Product Description: Immunotag™ SENP5 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | SENP5 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,IHC-p,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse,Monkey |
| Host Species | Rabbit |
| Immunogen | The antiserum was produced against synthesized peptide derived from human SENP5. AA range:651-700 |
| Specificity | SENP5 Polyclonal Antibody detects endogenous levels of SENP5 protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | SENP5 |
| Accession No. | Q96HI0 Q6NXL6 |
| Alternate Names | SENP5; FKSG45; Sentrin-specific protease 5; Sentrin/SUMO-specific protease SENP5 |
| Description | SUMO1/sentrin specific peptidase 5(SENP5) Homo sapiens The reversible posttranslational modification of proteins by the addition of small ubiquitin-like SUMO proteins (see SUMO1; MIM 601912) is required for numerous biologic processes. SUMO-specific proteases, such as SENP5, are responsible for the initial processing of SUMO precursors to generate a C-terminal diglycine motif required for the conjugation reaction. They also have isopeptidase activity for the removal of SUMO from high molecular mass SUMO conjugates (Di Bacco et al., 2006 [PubMed 16738315]).[supplied by OMIM, Jun 2009], |
| Protein Expression | Placenta,Testis, |
| Subcellular Localization | nucleus,nucleoplasm,nucleolus,intracellular membrane-bounded organelle, |
| Protein Function | function:Protease that catalyzes two essential functions in the SUMO pathway: processing of full-length SUMO3 to its mature form and deconjugation of SUMO2 and SUMO3 from targeted proteins. Has weak proteolytic activity against full-length SUMO1 or SUMO1 conjugates. Required for cell division.,similarity:Belongs to the peptidase C48 family., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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