ITT4249
ITT4249
- Catalog: ITT4249
- Gene/Protein: SEPT5
- Product Description: Immunotag™ Septin 5 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | Septin 5 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse,Rat |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from Septin 5, at AA range: 180-260 |
| Specificity | Septin 5 Polyclonal Antibody detects endogenous levels of Septin 5 protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | SEPT5 |
| Accession No. | Q99719 Q9Z2Q6 Q9JJM9 |
| Alternate Names | SEPT5; PNUTL1; Septin-5; Cell division control-related protein 1; CDCrel-1; Peanut-like protein 1 |
| Description | septin 5(SEPT5) Homo sapiens This gene is a member of the septin gene family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is mapped to 22q11, the region frequently deleted in DiGeorge and velocardiofacial syndromes. A translocation involving the MLL gene and this gene has also been reported in patients with acute myeloid leukemia. Alternative splicing results in multiple transcript variants. The presence of a non-consensus polyA signal (AACAAT) in this gene also results in read-through transcription into the downstream neighboring gene (GP1BB; platelet glycoprotein Ib), whereby larger, non-coding transcripts are produced. [provided by RefSeq, Dec 2010], |
| Cell Pathway/ Category | Parkinson's disease, |
| Protein Expression | Brain,Cajal-Retzius cell,Fetal brain cortex,Heart,Lung,Platelet, |
| Subcellular Localization | cytoskeleton,plasma membrane,cell cortex,synaptic vesicle,terminal bouton, |
| Protein Function | function:Involved in cytokinesis .,similarity:Belongs to the septin family.,subunit:May assemble into a multicomponent structure., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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