ITT4318
ITT4318
- Catalog: ITT4318
- Gene/Protein: SLC6A8
- Product Description: Immunotag™ SLC6A8 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
|
| Target Protein | SLC6A8 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse,Rat |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from SLC6A8, at AA range: 550-630 |
| Specificity | SLC6A8 Polyclonal Antibody detects endogenous levels of SLC6A8 protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | SLC6A8 |
| Accession No. | P48029 Q8VBW1 P28570 |
| Alternate Names | SLC6A8; Sodium- and chloride-dependent creatine transporter 1; CT1; Creatine transporter 1; Solute carrier family 6 member 8 |
| Description | solute carrier family 6 member 8(SLC6A8) Homo sapiens The protein encoded by this gene is a plasma membrane protein whose function is to transport creatine into and out of cells. Defects in this gene can result in X-linked creatine deficiency syndrome. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008], |
| Protein Expression | Brain,Brain hippocampus,Eye,Hippocampus,Kidney,Testis, |
| Subcellular Localization | plasma membrane,integral component of plasma membrane,integral component of membrane, |
| Protein Function | disease:Defects in SLC6A8 are the cause of X-linked creatine deficiency syndrome [MIM:300352]. X-linked creatine deficiency syndrome causes developmental delay, hypotonia, mental retardation, seizures, short stature and midface hypoplasia.,function:Required for the uptake of creatine in muscles and brain.,similarity:Belongs to the sodium:neurotransmitter symporter (SNF) family.,tissue specificity:Predominantly expressed in skeletal muscle and kidney. Also found in brain, heart, colon, testis and prostate., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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