ITT4361
ITT4361
- Catalog: ITT4361
- Gene/Protein: UBXN11
- Product Description: Immunotag™ Socius Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | Socius |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,IHC-p,IF,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human |
| Host Species | Rabbit |
| Immunogen | The antiserum was produced against synthesized peptide derived from human UBXD5. AA range:131-180 |
| Specificity | Socius Polyclonal Antibody detects endogenous levels of Socius protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | UBXN11 |
| Accession No. | Q5T124 Q9D572 |
| Alternate Names | UBXN11; SOC; UBXD5; PP2243; UBX domain-containing protein 11; Colorectal tumor-associated antigen COA-1; Socius; UBX domain-containing protein 5 |
| Description | UBX domain protein 11(UBXN11) Homo sapiens This gene encodes a protein with a divergent C-terminal UBX domain. The homologous protein in the rat interacts with members of the Rnd subfamily of Rho GTPases at the cell periphery through its C-terminal region. It also interacts with several heterotrimeric G proteins through their G-alpha subunits and promotes Rho GTPase activation. It is proposed to serve a bidirectional role in the promotion and inhibition of Rho activity through upstream signaling pathways. The 3' coding sequence of this gene contains a polymoprhic region of 24 nt tandem repeats. Several transcripts containing between 1.5 and five repeat units have been reported. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008], |
| Protein Expression | Colon cancer,Small intestine,Synovium,Testis, |
| Subcellular Localization | cytoplasm,cytoskeleton, |
| Protein Function | function:May be involved in the reorganization of actin cytoskeleton mediated by RND1, RND2 AND RND3. Promotes RHOA activation mediated by GNA12 and GNA13.,polymorphism:The number of repeats is polymorphic and varies from 1 to 4.,similarity:Contains 1 SEP domain.,similarity:Contains 1 UBX domain.,subunit:Interacts with GNA12, GNA13, RND1, RND2 AND RND3., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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