ITT4367
ITT4367
- Catalog: ITT4367
- Gene/Protein: SOS2
- Product Description: Immunotag™ Sos 2 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | SOS 2 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human |
| Host Species | Rabbit |
| Immunogen | The antiserum was produced against synthesized peptide derived from human SOS2. AA range:631-680 |
| Specificity | Sos 2 Polyclonal Antibody detects endogenous levels of Sos 2 protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | SOS2 |
| Accession No. | Q07890 Q02384 |
| Alternate Names | SOS2; Son of sevenless homolog 2; SOS-2 |
| Description | SOS Ras/Rho guanine nucleotide exchange factor 2(SOS2) Homo sapiens This gene encodes a regulatory protein that is involved in the positive regulation of ras proteins. Mutations in this gene are associated with Noonan Syndrome-9. [provided by RefSeq, Jul 2016], |
| Cell Pathway/ Category | MAPK_ERK_Growth,MAPK_G_Protein,ErbB_HER,Chemokine,Dorso-ventral axis formation,Focal adhesion,Gap junction,Jak_STAT,Natural killer cell mediated cytotoxicity,T_Cell_Receptor,B_Cell_Antigen,Fc epsilon RI,Neurotrophin,Regulates Actin and Cytoskeleton,Insulin_Receptor,GnRH,Pathways in cancer,Colorectal cancer,Renal cell carcinoma,Endometrial cancer,Glioma,Prostate cancer,Chronic myeloid leukemia,Acute myeloid leukemia,Non-small cell lung cancer, |
| Protein Expression | Brain,Placenta, |
| Subcellular Localization | intracellular,cytosol, |
| Protein Function | function:Promotes the exchange of Ras-bound GDP by GTP.,online information:Son of sevenless entry,similarity:Contains 1 DH (DBL-homology) domain.,similarity:Contains 1 N-terminal Ras-GEF domain.,similarity:Contains 1 PH domain.,similarity:Contains 1 Ras-GEF domain., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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