ITT4368
ITT4368
- Catalog: ITT4368
- Gene/Protein: SOX12
- Product Description: Immunotag™ Sox-12 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | SOX12 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | IHC-p,ELISA |
| Recommended Dilution | Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse |
| Host Species | Rabbit |
| Immunogen | The antiserum was produced against synthesized peptide derived from human SOX12. AA range:71-120 |
| Specificity | Sox-12 Polyclonal Antibody detects endogenous levels of Sox-12 protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | SOX12 |
| Accession No. | O15370 Q04890 |
| Alternate Names | SOX12; SOX22; Transcription factor SOX-12; Protein SOX-22 |
| Description | SRY-box 12(SOX12) Homo sapiens Members of the SOX family of transcription factors are characterized by the presence of a DNA-binding high mobility group (HMG) domain, homologous to the HMG box of sex-determining region Y (SRY). Forming a subgroup of the HMG domain superfamily, SOX proteins have been implicated in cell fate decisions in a diverse range of developmental processes. SOX transcription factors have diverse tissue-specific expression patterns during early development and have been proposed to act as target-specific transcription factors and/or as chromatin structure regulatory elements. The protein encoded by this gene was identified as a SOX family member based on conserved domains, and its expression in various tissues suggests a role in both differentiation and maintenance of several cell types. [provided by RefSeq, Jan 2013], |
| Protein Expression | Fetal brain,Prostate, |
| Subcellular Localization | nucleoplasm,protein-DNA complex, |
| Protein Function | function:Binds to the sequence 5'-AACAAT-3'.,similarity:Contains 1 HMG box DNA-binding domain.,tissue specificity:Expressed most abundantly in the CNS. Also expressed in fetal brain and kidney and adult heart, pancreas, testis and ovary. Other tissues were only weakly positive., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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