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ITT4370

ITT4370
ITT4370
  • Gene/Protein: SOX8/9/17/18
  • Product Description: Immunotag™ Sox-8/9/17/18 Polyclonal Antibody
  • 280.0000
    Price in reward points: 294

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ITT4370

Immunotag™ Sox-8/9/17/18 Polyclonal Antibody
Antibody Specification
Datasheet
Target Protein SOX8/9/17/18
Clonality Polyclonal
Storage/Stability -20°C/1 year
Application WB,IHC-p,ELISA
Recommended Dilution Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
Concentration 1 mg/ml
Reactive Species Human,Mouse,Monkey
Host Species Rabbit
Immunogen The antiserum was produced against synthesized peptide derived from human SOX8/9/17/18. AA range:116-165
Specificity Sox-8/9/17/18 Polyclonal Antibody detects endogenous levels of Sox-8/9/17/18 protein.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Gene Name SOX8/9/17/18
Accession No. P57073/P48436/Q9H6I2/P35713
Alternate Names SOX8; Transcription factor SOX-8; SOX9; Transcription factor SOX-9; SOX17; Transcription factor SOX-17; SOX18; Transcription factor SOX-18
Description SRY-box 8(SOX8) Homo sapiens This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional activator after forming a protein complex with other proteins. This protein may be involved in brain development and function. Haploinsufficiency for this protein may contribute to the mental retardation found in haemoglobin H-related mental retardation (ART-16 syndrome). [provided by RefSeq, Jul 2008],
Cell Pathway/ Category WNT,WNT-T CELL,β-Catenin
Protein Expression Brain,Spleen,
Subcellular Localization nucleus,cytoplasm,nuclear transcription factor complex,
Protein Function function:May play a role in central nervous system, limb and facial development. May be involved in male sex determination. Binds the consensus motif 5'-[AT][AT]CAA[AT]G-3'.,similarity:Contains 1 HMG box DNA-binding domain.,
Usage For Research Use Only! Not for diagnostic or therapeutic procedures.
Material Safety Data Sheet
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