ITT4419
ITT4419
- Catalog: ITT4419
- Gene/Protein: SRSF8
- Product Description: Immunotag™ SRp46 Polyclonal Antibody
385.0000
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Antibody Specification | |
Datasheet | |
Target Protein | SRp46 |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,IHC-p,ELISA |
Recommended Dilution | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications. |
Concentration | 1 mg/ml |
Reactive Species | Human |
Host Species | Rabbit |
Immunogen | The antiserum was produced against synthesized peptide derived from human SFRS2B. AA range:31-80 |
Specificity | SRp46 Polyclonal Antibody detects endogenous levels of SRp46 protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Gene Name | SRSF8 |
Accession No. | Q9BRL6 |
Alternate Names | SRSF8; SFRS2B; SRP46; Serine/arginine-rich splicing factor 8; Pre-mRNA-splicing factor SRP46; Splicing factor SRp46; Splicing factor; arginine/serine-rich 2B |
Description | serine and arginine rich splicing factor 8(SRSF8) Homo sapiens This gene encodes a member of a family of proteins containing a ribonucleoprotein (RNP)-type RNA binding motif and a carboxyl-terminal arginine-serine-rich (RS) domain. The encoded protein functions as a pre-mRNA splicing factor. There is a pseudogene for this gene on chromosome 7. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2013], |
Cell Pathway/ Category | Spliceosome, |
Protein Expression | Brain,Epithelium,Placenta,Thymus, |
Subcellular Localization | nucleus, |
Protein Function | function:Invovlved in pre-mRNA alternative splicing.,PTM:Phosphorylated.,similarity:Belongs to the splicing factor SR family.,similarity:Contains 1 RRM (RNA recognition motif) domain.,tissue specificity:Strongly expressed in pancreas, spleen and prostate. Weakly expressed in lung, liver and thymus., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |