ITT4420
ITT4420
- Catalog: ITT4420
- Gene/Protein: SRSF6
- Product Description: Immunotag™ SRp55 Polyclonal Antibody
385.0000
Price in reward points: 385
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Antibody Specification | |
Datasheet | |
Target Protein | SRp55 |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | IHC-p,ELISA |
Recommended Dilution | Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications. |
Concentration | 1 mg/ml |
Reactive Species | Human,Mouse,Rat |
Host Species | Rabbit |
Immunogen | Synthesized peptide derived from SRp55 . at AA range: 30-110 |
Specificity | SRp55 Polyclonal Antibody detects endogenous levels of SRp55 protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Gene Name | SRSF6 |
Accession No. | Q13247 |
Alternate Names | SRSF6; SFRS6; SRP55; Serine/arginine-rich splicing factor 6; Pre-mRNA-splicing factor SRP55; Splicing factor; arginine/serine-rich 6 |
Description | serine and arginine rich splicing factor 6(SRSF6) Homo sapiens The protein encoded by this gene is involved in mRNA splicing and may play a role in the determination of alternative splicing. The encoded nuclear protein belongs to the splicing factor SR family and has been shown to bind with and modulate another member of the family, SFRS12. Alternative splicing results in multiple transcript variants. In addition, two pseudogenes, one on chromosome 17 and the other on the X chromosome, have been found for this gene.[provided by RefSeq, Sep 2010], |
Cell Pathway/ Category | Spliceosome, |
Protein Expression | Brain,Colon,Epithelium,Placenta, |
Subcellular Localization | nucleoplasm,nuclear speck, |
Protein Function | function:Plays a role in constitutive splicing and can modulate the selection of alternative splice sites.,PTM:Extensively phosphorylated on serine residues in the RS domain.,similarity:Belongs to the splicing factor SR family.,similarity:Contains 2 RRM (RNA recognition motif) domains.,subunit:Binds SFRS12., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |