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ITT4488

ITT4488
ITT4488
ITT4488
  • Catalog: ITT4488
  • Gene/Protein: SYT13
  • Product Description: Immunotag™ Synaptotagmin XIII Polyclonal Antibody
385.0000
Price in reward points: 385

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Immunotag™ Synaptotagmin XIII Polyclonal Antibody
Antibody Specification
Datasheet
Target Protein Synaptotagmin XIII
Clonality Polyclonal
Storage/Stability -20°C/1 year
Application WB,ELISA
Recommended Dilution Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Concentration 1 mg/ml
Reactive Species Human,Mouse,Rat
Host Species Rabbit
Immunogen Synthesized peptide derived from Synaptotagmin XIII, at AA range: 290-370
Specificity Synaptotagmin XIII Polyclonal Antibody detects endogenous levels of Synaptotagmin XIII protein.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Gene Name SYT13
Accession No. Q7L8C5 Q9EQT6 Q925B5
Alternate Names SYT13; KIAA1427; Synaptotagmin-13; Synaptotagmin XIII; SytXIII
Description synaptotagmin 13(SYT13) Homo sapiens This gene encodes a member of the large synaptotagmin protein family. Family members have an extracellular N-terminal transmembrane domain and a cytoplasmic C terminus with two tandem C2 domains (C2A and C2B). Synaptotogmin family members can form homo- and heteromeric complexes with each other. They also have different biochemical properties and developmental profiles, and patterns of tissue distribution. Synaptotagmins function as membrane traffickers in multicellular organisms. Two alternatively spliced transcript variants that encode different protein isoforms have been described for this gene. [provided by RefSeq, Oct 2011],
Protein Expression Brain,Fetal brain,
Subcellular Localization plasma membrane,integral component of plasma membrane,transport vesicle,intracellular membrane-bounded organelle,presynapse,
Protein Function domain:The first C2 domain/C2A does not mediate Ca(2+)-dependent phospholipid binding.,domain:The second C2 domain/C2B domain binds phospholipids regardless of whether calcium is present.,function:May be involved in transport vesicle docking to the plasma membrane.,similarity:Belongs to the synaptotagmin family.,similarity:Contains 2 C2 domains.,subunit:Interacts with NRXN1.,tissue specificity:Expressed in brain, pancreas and kidney.,
Usage For Research Use Only! Not for diagnostic or therapeutic procedures.
Material Safety Data Sheet
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