ITT4491
ITT4491
- Catalog: ITT4491
- Gene/Protein: SDC4
- Product Description: Immunotag™ Syndecan-4 Polyclonal Antibody
385.0000
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Antibody Specification | |
Datasheet | |
Target Protein | Syndecan-4 |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,IHC-p,IF,ELISA |
Recommended Dilution | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications. |
Concentration | 1 mg/ml |
Reactive Species | Human,Mouse,Rat |
Host Species | Rabbit |
Immunogen | Synthesized peptide derived from Syndecan-4, at AA range: 120-200 |
Specificity | Syndecan-4 Polyclonal Antibody detects endogenous levels of Syndecan-4 protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Gene Name | SDC4 |
Accession No. | P31431 O35988 P34901 |
Alternate Names | SDC4; Syndecan-4; SYND4; Amphiglycan; Ryudocan core protein |
Description | syndecan 4(SDC4) Homo sapiens The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan that functions as a receptor in intracellular signaling. The encoded protein is found as a homodimer and is a member of the syndecan proteoglycan family. This gene is found on chromosome 20, while a pseudogene has been found on chromosome 22. [provided by RefSeq, Jul 2008], |
Cell Pathway/ Category | ECM-receptor interaction,Cell adhesion molecules (CAMs), |
Protein Expression | Lung,Lung fibroblast,Placenta,Stomach,Thalamus, |
Subcellular Localization | Golgi lumen,plasma membrane,integral component of plasma membrane,focal adhesion,cell surface,integral component of membrane,costamere,lysosomal lumen,membrane raft,extracellular exosome, |
Protein Function | function:Cell surface proteoglycan that bears heparan sulfate.,function:Cell surface proteoglycan.,similarity:Belongs to the syndecan proteoglycan family.,subunit:Homodimer. Interacts with CDCP1, with GIPC PDZ domain and with NUDT16L1/SDOS (By similarity). Interacts with SDCBP.,tissue specificity:Expressed in epithelial and fibroblastic cells., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |