ITT4507
ITT4507
- Catalog: ITT4507
- Gene/Protein: TAS2R16
- Product Description: Immunotag™ T2R16 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | T2R16 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,IF,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human |
| Host Species | Rabbit |
| Immunogen | The antiserum was produced against synthesized peptide derived from human TAS2R16. AA range:136-185 |
| Specificity | T2R16 Polyclonal Antibody detects endogenous levels of T2R16 protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | TAS2R16 |
| Accession No. | Q9NYV7 P59529 |
| Alternate Names | TAS2R16; Taste receptor type 2 member 16; T2R16 |
| Description | taste 2 receptor member 16(TAS2R16) Homo sapiens This gene encodes a member of a family of candidate taste receptors that are members of the G protein-coupled receptor superfamily. These family members are specifically expressed by taste receptor cells of the tongue and palate epithelia. Each of these apparently intronless genes encodes a 7-transmembrane receptor protein, functioning as a bitter taste receptor. This gene is clustered with another 3 candidate taste receptor genes in chromosome 7 and is genetically linked to loci that influence bitter perception. [provided by RefSeq, Jul 2008], |
| Cell Pathway/ Category | Taste transduction, |
| Subcellular Localization | endoplasmic reticulum,trans-Golgi network,plasma membrane,external side of plasma membrane,integral component of membrane, |
| Protein Function | function:Gustducin-coupled receptor implicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract. Signals through PLCB2 and the calcium-regulated cation channel TRPM5.,miscellaneous:Confers bitter perception of salicin to non-taster mice.,miscellaneous:Several bitter taste receptors are expressed in a single taste receptor cell.,polymorphism:The Lys-172 polymorphism in TAS2R16 is associated with genetic susceptibility to alcoholism [MIM:103780].,similarity:Belongs to the G-protein coupled receptor T2R family.,tissue specificity:Expressed in a subset of gustducin-positive taste receptor cells of the tongue., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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