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ITT4508

ITT4508
  • Gene/Protein: TAS2R3
  • Product Description: Immunotag™ T2R3 Polyclonal Antibody
280.0000
Price in reward points: 294

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Immunotag™ T2R3 Polyclonal Antibody
Antibody Specification
Datasheet
Target Protein T2R3
Clonality Polyclonal
Storage/Stability -20°C/1 year
Application IF,ELISA
Recommended Dilution Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
Concentration 1 mg/ml
Reactive Species Human
Host Species Rabbit
Immunogen The antiserum was produced against synthesized peptide derived from human TAS2R3. AA range:140-189
Specificity T2R3 Polyclonal Antibody detects endogenous levels of T2R3 protein.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Gene Name TAS2R3
Accession No. Q9NYW6 Q7TQA7
Alternate Names TAS2R3; Taste receptor type 2 member 3; T2R3
Description taste 2 receptor member 3(TAS2R3) Homo sapiens This gene encodes a member of a family of candidate taste receptors that are members of the G protein-coupled receptor superfamily and that are specifically expressed by taste receptor cells of the tongue and palate epithelia. These apparently intronless taste receptor genes encode a 7-transmembrane receptor protein, functioning as a bitter taste receptor. This gene is clustered with another 3 candidate taste receptor genes in chromosome 7 and is genetically linked to loci that influence bitter perception. [provided by RefSeq, Jul 2008],
Cell Pathway/ Category Taste transduction,
Subcellular Localization plasma membrane,integral component of membrane,
Protein Function function:Gustducin-coupled receptor implicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract. Signals through PLCB2 and the calcium-regulated cation channel TRPM5.,miscellaneous:Several bitter taste receptors are expressed in a single taste receptor cell.,similarity:Belongs to the G-protein coupled receptor T2R family.,tissue specificity:Expressed in subsets of taste receptor cells of the tongue and palate epithelium and exclusively in gustducin-positive cells. Expressed in the antrum and fundus (part of the stomach), duodenum and in gastric endocrine cells.,
Usage For Research Use Only! Not for diagnostic or therapeutic procedures.
Material Safety Data Sheet
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