ITT4520
ITT4520
- Catalog: ITT4520
- Gene/Protein: TNKS1BP1
- Product Description: Immunotag™ TAB182 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
|
| Target Protein | TAB182 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse |
| Host Species | Rabbit |
| Immunogen | The antiserum was produced against synthesized peptide derived from human TNKS1BP1. AA range:1601-1650 |
| Specificity | TAB182 Polyclonal Antibody detects endogenous levels of TAB182 protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | TNKS1BP1 |
| Accession No. | Q9C0C2 P58871 |
| Alternate Names | TNKS1BP1; KIAA1741; TAB182; 182 kDa tankyrase-1-binding protein |
| Description | PTM:ADP-ribosylated by TNKS1 (in vitro).,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,subcellular location:Colocalizes with chromosomes during mitosis, and in the cytoplasm with cortical actin.,subunit:Binds to the ANK repeat domain of TNKS1 and TNKS2.,tissue specificity:Detected in testis, ovary, lung, skeletal muscle, heart, prostate and pancreas, and at very low levels in brain and peripheral blood leukocytes., |
| Protein Expression | Brain,Epithelium,Hippocampus,Liver,Peripheral Nervous System,Placenta,Skin, |
| Subcellular Localization | nucleus,nucleoplasm,nuclear telomeric heterochromatin,cytoplasm,cytosol,cytoskeleton,plasma membrane,cell-cell adherens junction,CCR4-NOT complex, |
| Protein Function | PTM:ADP-ribosylated by TNKS1 (in vitro).,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,subcellular location:Colocalizes with chromosomes during mitosis, and in the cytoplasm with cortical actin.,subunit:Binds to the ANK repeat domain of TNKS1 and TNKS2.,tissue specificity:Detected in testis, ovary, lung, skeletal muscle, heart, prostate and pancreas, and at very low levels in brain and peripheral blood leukocytes., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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