ITT4569
ITT4569
- Catalog: ITT4569
- Gene/Protein: TBX2/TBX3
- Product Description: Immunotag™ TBX2/3 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | TBX2/3 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse,Rat |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from TBX2/3, at AA range: 240-320 |
| Specificity | TBX2/3 Polyclonal Antibody detects endogenous levels of TBX2/3 protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | TBX2/TBX3 |
| Accession No. | O15119/Q13207 Q7TST9 |
| Alternate Names | TBX3; T-box transcription factor TBX3; T-box protein 3; TBX2; T-box transcription factor TBX2; T-box protein 2 |
| Description | T-box 3(TBX3) Homo sapiens This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This protein is a transcriptional repressor and is thought to play a role in the anterior/posterior axis of the tetrapod forelimb. Mutations in this gene cause ulnar-mammary syndrome, affecting limb, apocrine gland, tooth, hair, and genital development. Alternative splicing of this gene results in three transcript variants encoding different isoforms; however, the full length nature of one variant has not been determined. [provided by RefSeq, Jul 2008], |
| Protein Expression | Adrenal gland,Brain,Epithelium,Kidney,Mammary carcinoma, |
| Subcellular Localization | nucleus, |
| Protein Function | disease:Defects in TBX3 are the cause of ulnar-mammary syndrome (UMS) [MIM:181450]. UMS is characterized by ulnar ray defects, obesity, hypogenitalism, delayed puberty, hypoplasia of nipples and apocrine glands.,function:Transcriptional repressor involved in developmental processes. Probably plays a role in limb pattern formation.,similarity:Contains 1 T-box DNA-binding domain.,tissue specificity:Widely expressed., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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